Take 1-3 droppers full (each dropper fills up 50-75%), under the tongue 1-3 times per day, or as recommended by your health care professional or personally desired. Hold under your tongue for 15 seconds before swallowing, apply topically, or add to food and or drink. 120 droppers per bottle. Effects are more noticeable on an empty stomach. Great to use before physical activities like exercise and intimacy, or in replacement of coffee.